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Updated: Jun 4, 2025
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Objectively Assessing Sports Concussion Utilizing Visual Evoked Potentials
Published on: April 27, 2021
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Quantitative pupillometry as a potential biomarker in early concussion assessment
Moez M I Bashir1, DaiWai M Olson2, Natassia T Miller3
1Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Summary
Quantitative pupillometry (QP) offers objective metrics for concussion evaluation, unlike subjective methods. Specific QP values may help assess concussion symptom severity and aid in diagnosis.
Area of Science:
- Neurology
- Sports Medicine
- Ophthalmology
Background:
- Concussion diagnosis lacks objective measures.
- Pupil assessment is standard post-TBI but often unreliable.
- Quantitative pupillometry (QP) provides a valid and reliable method for pupillary assessment.
Purpose of the Study:
- To investigate the utility of QP values in concussion evaluation.
- To explore objective metrics for concussion diagnosis.
- To correlate QP findings with concussion symptom severity.
Main Methods:
- Observational study using data from the North Texas Concussion Registry (ConTex).
- Included 162 subjects clinically diagnosed with concussion, excluding severe TBI.
- Collected demographics, injury history, SCAT5 PCSS scores, and QP data using a handheld pupillometer.
Main Results:
- Mean age 15.8 years, 54.3% female; 49.4% sport-related injuries.
- Significant differences in constriction velocities found between early (<2 weeks) and late (>2 weeks) post-injury assessments.
- Pupillometry values differed significantly across concussion symptom severity tertiles.
Conclusions:
- Certain QP values, including constriction and dilation velocities, show potential as objective metrics.
- QP may provide valuable objective data for evaluating symptomatic concussions.
- This exploratory study highlights QP's role in enhancing concussion assessment.
