Related Experiment Video
Updated: May 7, 2025
Mouse Model of Oleic Acid-Induced Acute Respiratory Distress Syndrome
Published on: June 2, 2022
Association between C-reactive protein to albumin ratio and chronic obstructive pulmonary disease: a cross-sectional
Ting Ao1, Yingxiu Huang1, Peng Zhen1
1Department of Infectious Diseases, Beijing Luhe Hospital, Capital Medical University, No.82, Xinhua South Road, Tongzhou District, Beijing, 101100, China.
Background:
Chronic obstructive pulmonary disease (COPD) is a widespread condition that significantly endangers human health. The C-reactive protein to albumin ratio (CAR) has been utilized as an important marker for the occurrence and development of various diseases. Nevertheless, the association between CAR and COPD remains inadequately explored. This research aimed to examine the link between the CAR and COPD.
Methods:
This cross-sectional study examined data from adult participants in the National Health and Nutrition Examination Survey between 1999 and 2010. The identification of COPD relied on data obtained directly from self-reported information. Logistic regression analysis was used to estimate the odds ratio (OR) and 95% confidence interval (CI) for the association between CAR and COPD. Additionally, subgroup and sensitivity analyses were performed to evaluate the stability of the observed relationship.
Results:
The study comprised 24,627 participants, among whom 1,809 had COPD. After adjusting for potential confounders, CAR was found to be associated with COPD (OR 1.37; 95% CI, 1.12-1.69; P = 0.003). In the analysis comparing individuals in the lowest CAR tertile (T1) with those in the highest, the adjusted OR for COPD was 1.39 (95% CI, 1.17-1.65; P < 0.001). Validation through subgroup and sensitivity analyses further strengthened the stability and consistency of the study's findings.
Conclusion:
Elevated levels of the CAR were correlated with an increased risk of COPD.
Clinical Trial Number:
not applicable.
More Related Videos
04:53Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD — A Safe, Cost-Effective Approach
Published on: October 18, 2024
08:44Author Spotlight: Integrating Alveolar-Capillary Reserve Measurements in Exercise Adaptation and Therapeutic Strategies
Published on: February 2, 2024
Related Concept Videos
01:20Chronic Obstructive Pulmonary Disease-II: Pathophysiology
Chronic Inflammation
01:20Chronic Obstructive Pulmonary Disease-I: Introduction
01:27Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
Medical History
01:30Pneumonia III: Complications and Assessment
01:25Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
01:22Chronic Obstructive Pulmonary Disease
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...