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Dental maxillary sinus pathology: a CBCT-based case-control study
João Carlos Monteiro Castro1, José Luiz Cintra Junqueira1, Cleomar Donizeth Rodrigues2
1Division of Oral Radiology, Faculdade São Leopoldo Mandic, Rua Dr. José Rocha Junqueira 13 Campinas, São Paulo, 13045-755, Brazil.
Odontology
|January 4, 2025
Summary
Dental infections like apical periodontitis (AP) and endoperiodontal lesions (EPL) significantly increase the risk of maxillary sinus pathology. Male sex also correlates with higher chances of sinus issues, independent of dental factors.
Area of Science:
- Dentistry
- Otolaryngology
- Radiology
Background:
- Dental infections, particularly apical periodontitis (AP) and endoperiodontal lesions (EPL), are potential sources of maxillary sinus pathology.
- Understanding the factors influencing this association is crucial for diagnosis and treatment.
Purpose of the Study:
- To evaluate the link between dental infections and maxillary sinus pathology.
- To determine the influence of patient demographics and anatomical factors on this association.
Main Methods:
- Computed Tomography (CT) scans were used to assess dental conditions (AP, EPL) and sinus pathology (mucosal thickening - MT, opacification of the maxillary sinus - OMS).
- Logistic regression, Chi-squared, and Fisher's tests were employed to analyze the data.
- Factors analyzed included age, sex, tooth type, root proximity to the sinus floor, and ostium condition.
Main Results:
- Patients with AP were significantly more likely to have MT (15.63 times) and OMS (25.97 times).
- EPL showed a strong association with OMS.
- Male patients had a higher likelihood of developing MT (1.30 times) and OMS (5.86 times) compared to females.
Conclusions:
- Male sex, apical periodontitis (AP), and endoperiodontal lesions (EPL) are significantly associated with maxillary sinus pathology.
- Factors such as ostium condition, accessory ostium presence, tooth type, and root proximity did not show a significant association.

