Newer Biomarkers in Gallbladder Carcinoma: A Scoping Review

Biomarkers have the potential to play a crucial role in managing gallbladder cancer post-surgery. They can identify patients more likely to experience a recurrence, allowing oncologists to tailor a more intensive surveillance plan and consider additional therapies. Some biomarkers can even predict how well a patient will respond to specific chemotherapy or targeted treatments. By monitoring these biomarkers, clinicians can track how effective the ongoing treatment is and detect any signs of early recurrence. Various biomarkers, like tumor markers, genetic markers, and genomic and epigenetic markers, are being investigated. The goal is to find the most reliable and accurate biomarkers to enhance patient care and outcomes. Integrating biomarker data into treatment plans can help personalize therapy and make better informed decisions. By identifying which patients are likely to benefit from specific treatments, biomarkers have the potential to improve long-term survival rates significantly. This scoping review discusses newer biomarkers in gallbladder carcinoma; some of them are in clinical use, while most of them are used in research settings. This provides a broad insight to practicing clinicians about the present biomarkers and the futuristic biomarkers.