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Updated: Jun 3, 2025

Chemoselective Modification of Viral Surfaces via Bioorthogonal Click Chemistry
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Direct Click Bonding of Dissimilar Solid Materials Based on the Catalyst-Free Huisgen 1,3-Dipolar Cycloaddition

Yusuke Kanki1, Koki Miyahara1, Shota Yamamoto1

  • 1Department of Chemical Science and Engineering, Graduate School of Engineering, Kobe University, 1-1 Rokkodai, Nada-ku, Kobe, 657-8501, Japan.

Macromolecular Rapid Communications
|January 9, 2025
PubMed
Summary

Direct click bonding forms strong covalent bonds between solid surfaces without adhesives. This novel method uses a copper-free cycloaddition reaction, offering controllable, durable, and versatile material joining under ambient conditions.

Keywords:
Cu‐free click reactionadhesive bondingpolymer coatingsolid–solid interfacesurface density

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