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Updated: May 12, 2026

Solid-phase Synthesis of [4.4] Spirocyclic Oximes
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A Synthetic Method for Spirocyclobutanes via Ring Expansion of Donor-Acceptor Spirocyclopropanes with Stabilized

Kota Yoshioka1, Rika Sakai1, Hikaru Fujii1

  • 1Laboratory of Pharmaceutical Synthetic Chemistry, Kyoto Pharmaceutical University, Kyoto 607-8412, Japan.

The Journal of Organic Chemistry
|May 10, 2026
PubMed

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