A Large Study About Reproductive Factors That Predict Hysterosalpingography-Identified Tubal Pathology: An Insight...

Area of Science:

• Reproductive medicine
• Gynecological imaging
• Infertility diagnostics

Background:

• Hysterosalpingography (HSG) is crucial for diagnosing tubal pathology but involves pain and radiation.
• Identifying predictive factors for HSG findings can optimize diagnostic strategies.

Purpose of the Study:

• To investigate reproductive and clinical factors that predict tubal pathology detected via hysterosalpingography (HSG).

Main Methods:

• Retrospective analysis of 3322 infertile females undergoing HSG between May 2016 and August 2023.
• Multivariate logistic regression was used to identify predictors of non-patent tubes, occlusion, and hydrosalpinx.

Main Results:

• 16.8% of participants had non-patent tubes. Chlamydia trachomatis IgG positivity, endometrioma, and fibroids predicted non-patency.
• Chlamydia trachomatis IgG positivity and fibroids were risk factors for tubal occlusion.
• Painful defecation, Chlamydia trachomatis IgA/IgG positivity, and endometrioma predicted hydrosalpinx.

Conclusions:

• Factors including Chlamydia trachomatis positivity, endometrioma, and fibroids are associated with HSG-identified tubal pathology.
• In specific patient groups (e.g., painful defecation), HSG can be a second-line test, with laparoscopy as the primary diagnostic method.