Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Renal Corpuscle01:20

Renal Corpuscle

1.6K
The glomerulus and Bowman's capsule are two essential components of the nephron, which is the functional unit of the kidney. These microscopic structures play a critical role in the process of blood filtration to produce urine.
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous...
1.6K
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

55
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
55

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Narrative Review of C3 Glomerulopathy: From Pathogenesis to Targeted Therapy.

Canadian journal of kidney health and disease·2026
Same author

Canadian Society of Nephrology Commentary on the Evolving Kidney Disease Improving Global Outcomes Adult Glomerulonephritis Guidelines.

Canadian journal of kidney health and disease·2026
Same author

Comment on: Short and long-term outcomes of patients with pure membranous lupus nephritis compared to patients with proliferative disease: reply.

Rheumatology (Oxford, England)·2026
Same author

Postoperative Bilateral Renal Cortical Necrosis Secondary to Antiphospholipid Syndrome: A Case Report and Literature Review.

Canadian journal of kidney health and disease·2025
Same author

Insights into Geographic Patterns, Urban-Rural Contrasts, and Health Care Disparities in Glomerular Disease Incidence in a Canadian Province.

Kidney medicine·2025
Same author

Methotrexate-Associated Primary Cutaneous Epstein-Barr Virus-Positive Polymorphic B-Cell Lymphoproliferative Disorder With Metachronous T-Cell Clonally Related Angioimmunoblastic T-Cell Lymphoma: A Case Report and Review of the Literature.

The American Journal of dermatopathology·2025

Related Experiment Video

Updated: Jun 2, 2025

Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice
09:43

Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice

Published on: June 8, 2022

2.8K

Lupus nephritis: Biomarkers.

Chrisanna Dobrowolski1, Shu Min Lao1, Fadi Kharouf2

  • 1Division of Rheumatology, Department of Medicine, Mount Sinai School of Medicine, New York, NY, United States.

Advances in Clinical Chemistry
|January 16, 2025
PubMed
Summary

Lupus nephritis (LN), a kidney complication of systemic lupus erythematosus (SLE), affects many patients and can lead to severe outcomes. Recent advances offer new hope for understanding and treating this complex condition.

Keywords:
BiomarkersGeneticsGlomerulonephritis (GN)ImmunosuppressionLupus nephritis (LN)Systemic lupus erythematosus (SLE)

More Related Videos

The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice
12:04

The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice

Published on: November 1, 2015

17.4K
A Quantitative Detection Method for MicroRNAs in the Kidney of an Ischemic Kidney Injury Mouse Model
07:11

A Quantitative Detection Method for MicroRNAs in the Kidney of an Ischemic Kidney Injury Mouse Model

Published on: September 11, 2020

1.4K

Related Experiment Videos

Last Updated: Jun 2, 2025

Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice
09:43

Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice

Published on: June 8, 2022

2.8K
The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice
12:04

The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice

Published on: November 1, 2015

17.4K
A Quantitative Detection Method for MicroRNAs in the Kidney of an Ischemic Kidney Injury Mouse Model
07:11

A Quantitative Detection Method for MicroRNAs in the Kidney of an Ischemic Kidney Injury Mouse Model

Published on: September 11, 2020

1.4K

Area of Science:

  • Nephrology
  • Rheumatology
  • Immunology

Background:

  • Lupus nephritis (LN) is a common and serious complication of systemic lupus erythematosus (SLE), affecting over 50% of patients.
  • LN significantly contributes to morbidity, progressive renal dysfunction, and mortality in SLE patients.
  • Despite challenges, recent years have seen progress in understanding LN's pathogenesis and genetics.

Purpose of the Study:

  • To provide a foundational understanding of lupus nephritis (LN) pathogenesis, diagnosis, and epidemiology.
  • To review recent advancements in biomarkers and genetic susceptibility related to LN.
  • To guide readers through the complexities of this intricate renal condition.

Main Methods:

  • Literature review and synthesis of current knowledge on lupus nephritis.
  • Analysis of recent research on LN pathogenesis and genetic factors.
  • Compilation of data on diagnostic approaches and epidemiological trends.

Main Results:

  • Significant expansion in available LN treatments over the past decade.
  • Advances in understanding the genetic underpinnings of LN.
  • Emerging insights into LN pathogenesis and diagnostic biomarkers.

Conclusions:

  • Continued research into LN pathogenesis, genetics, and biomarkers is crucial.
  • Recent therapeutic advances offer improved management options for LN.
  • A comprehensive understanding of LN is essential for improved patient outcomes.