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A Protocol for Measuring Cue Reactivity in a Rat Model of Cocaine Use Disorder
Published on: June 18, 2018
Social Epidemiological Mediators of Rural and Urban Differences in Perceived Need for Cocaine Use Treatment
Tyrone F Borders1, Brenda M Booth2, Geoffrey M Curran3
1College of Nursing, University of Kentucky, Lexington, Kentucky.
None:
Rural/urban disparities in cocaine use treatment are commonly attributed to variations in social epidemiological constructs, such as socioeconomic status and well-being, social capital and support, and discrimination, as well as health care attitudes and health beliefs. This study examined whether these factors mediate rural vs. urban disparities in perceived need for cocaine use treatment, a concept closely linked to treatment utilization. Data were collected from 200 rural and 200 urban African American/Black persons who were active cocaine users and not in treatment. A multiple mediation model using path analysis was estimated to determine whether Addiction Severity Index (ASI) employment and legal scores, community trust, social support, rejection/discrimination, religious coping, medical skepticism, perceived treatment privacy and effectiveness, and Patient Health Questionaire-9 (PHQ-9) depression scores were mediators of the association between rural/urban residence and perceived treatment need. The total indirect effect of the multiple mediators was significant (unstandardized bootstrapped estimate of 0.444 and 95% CI of 0.11, 0.81). Unstandardized bootstrapped estimates for individual significant (p < .05) mediators were as follows: ASI employment scores (-0.114), ASI legal scores (0.146), perceived treatment effectiveness (0.294), and PHQ-9 scores (0.113). To further reduce rural and urban disparities in perceived need for treatment, policymakers, treatment managers, and providers might consider programs that address cocaine users' underlying social epidemiological differences.
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