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Protein N-terminal modifications: molecular machineries and biological implications

Hanne Øye1, Malin Lundekvam1, Alessia Caiella1

  • 1Department of Biomedicine, University of Bergen, Bergen, Norway.

Trends in Biochemical Sciences
|January 21, 2025
PubMed
Summary

Eukaryotic proteins undergo N-terminal (Nt) modifications by enzymes, impacting protein function and biological processes. This review covers Nt modifications, their enzymes, and their roles in health and disease.

Keywords:
acetylationarginylationmethylationmyristoylationoxidationubiquitylation

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