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Gemcitabine-induced myositis in a patient with pancreatic cancer
Zach Rubnitz1, Chris Nevala-Plagemann2, Vaia Florou2
1Internal Medicine, University of Utah Health, Salt Lake City, Utah, USA Zach.Rubnitz@hsc.utah.edu.
Abstract:
Gemcitabine, a cytosine analogue, is a cytotoxic agent commonly used in the treatment of patients with a variety of solid tumours, including non-small cell lung cancer, cholangiocarcinoma and breast, pancreatic, testicular and ovarian cancers. Although generally well-tolerated, several reports suggest that it can rarely cause myositis. We present a case of gemcitabine-induced myositis in a patient with pancreatic adenocarcinoma and review the literature on this topic.
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