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Risk Factors for Treatment Toxicity and High Side Effect Burden Among Breast Cancer Survivors: A Retrospective Chart
Muna Alkhaifi1, Elwyn Zhang1, Malika Peera2
1Department of Medical Oncology & Hematology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON M4N 3M5, Canada.
Breast cancer survivors frequently experience side effects impacting quality of life. Younger age and smoking are linked to higher symptom burden, necessitating tailored survivorship resources and smoking cessation support.
Area of Science:
- Oncology
- Cancer Survivorship
- Public Health
Background:
- Breast cancer survivorship clinics address long-term sequelae and toxicities.
- Understanding side effect burden is crucial for improving quality of life post-treatment.
Purpose of the Study:
- To describe side effects and toxicities in Canadian breast cancer survivors.
- To identify risk factors associated with increased side effect burden.
Main Methods:
- Retrospective chart review of 435 adult patients at a tertiary academic cancer centre's survivorship clinic.
- Data collected from July 2022 to September 2023.
Main Results:
- 72.6% of patients reported at least one side effect; 55.4% reported two or more.
- Common symptoms include anxiety, chronic pain, hot flashes, and fear of recurrence.
- Younger age, chemotherapy, and current smoking were associated with higher side effect burden.
Conclusions:
- Survivorship resources should be tailored for patients under 55.
- Smoking cessation programs are important for breast cancer survivors.
- Further research needed on patient discharge reluctance and younger survivor needs.
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