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Updated: May 29, 2025

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
Published on: October 11, 2018
When selection becomes selection bias
Kristina Laugesen1,2, Olaf M Dekkers1,3, Rolf H H Groenwold3
1Department of Clinical Epidemiology, Aarhus University and Aarhus University Hospital, 8200 Aarhus, Denmark.
None:
Selection in clinical research does not necessarily result in selection bias. To understand when selection leads to bias, we discuss collider-conditioning bias, which is a common and often self-inflicted type of selection bias. Collider-conditioning bias may be difficult to recognize, and paying more attention to the bias could therefore increase the quality of research. In this paper, we aim to increase awareness and understanding of the topic.
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