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Candida auris Diagnostics: Identification and Screening.

Erika P Orner1, Phyu M Thwe1

  • 1Department of Pathology, Montefiore Medical Center, 111 East 210th Street, Bronx, NY 10467, USA.

Clinics in Laboratory Medicine
|February 1, 2025
PubMed
Summary

Accurate detection of Candida auris (C. auris), an urgent threat yeast, is vital for control. This review examines current diagnostics and screening, highlighting needs for improved methods to combat C. auris spread and resistance.

Keywords:
Antifungal resistanceCandida aurisDiagnostic testScreening test

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Area of Science:

  • Medical Mycology
  • Infectious Diseases
  • Clinical Diagnostics

Background:

  • Candida auris is an emerging fungal pathogen identified as an urgent threat by the CDC.
  • This yeast exhibits significant antifungal resistance, high mortality rates, and efficient healthcare-associated transmission.
  • Effective containment and patient management necessitate precise and timely C. auris detection.

Purpose of the Study:

  • To review existing diagnostic methods for Candida auris detection.
  • To assess current screening guidelines for C. auris.
  • To identify critical areas for advancement in C. auris diagnostics.

Main Methods:

  • Literature review of current diagnostic technologies for C. auris.
  • Analysis of published screening protocols and recommendations.
  • Identification of gaps and limitations in existing diagnostic and screening strategies.

Main Results:

  • Current diagnostics for C. auris vary in sensitivity and specificity.
  • Screening guidance is evolving but requires further refinement.
  • There is a need for more rapid, accurate, and accessible diagnostic tools for C. auris.

Conclusions:

  • Improved diagnostics are essential for controlling the spread of C. auris.
  • Enhanced screening strategies can aid in early identification and intervention.
  • Further research and development are needed to address the diagnostic challenges posed by C. auris.