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Pyoderma Gangrenosum with Oral Involvement and Multidisciplinary Management
Héric de Souza Camargo1, Carolina da Silva Nunes1, Claudia Maria Navarro1
1Department of Diagnosis and Surgery, School of Dentistry, São Paulo State University (Unesp), Rua Humaitá, 1980, Centro, Araraquara, São Paulo CEP 14801-903 Brazil.
Introduction:
Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis often associated with inflammatory bowel disease.
Case Report:
We present a case of PG affecting the oral mucosa in a 31-year-old female with ulcerative colitis, necessitating total colectomy due to aggressive lesion progression. Despite initial adalimumab treatment, the lesions persisted, prompting a multidisciplinary approach. Following surgical intervention, including total colectomy and microvascularized graft with a forearm flap, the patient remained recurrence-free during a seven-year follow-up.
Conclusion:
This case underscores the complexity of PG and highlights the efficacy of a comprehensive therapeutic approach, emphasizing the importance of individualized management strategies in severe cases.
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