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Pyoderma Gangrenosum with Oral Involvement and Multidisciplinary Management.
Héric de Souza Camargo1, Carolina da Silva Nunes1, Claudia Maria Navarro1
1Department of Diagnosis and Surgery, School of Dentistry, São Paulo State University (Unesp), Rua Humaitá, 1980, Centro, Araraquara, São Paulo CEP 14801-903 Brazil.
Journal of Maxillofacial and Oral Surgery
|February 4, 2025
Summary
Pyoderma gangrenosum (PG) is a rare condition. This case shows surgery and multidisciplinary care successfully managed severe oral PG in an ulcerative colitis patient.
Area of Science:
- Dermatology
- Gastroenterology
- Surgical Oncology
Background:
- Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis.
- PG is frequently associated with inflammatory bowel disease (IBD).
Purpose of the Study:
- To present a complex case of oral pyoderma gangrenosum.
- To highlight the management of severe PG in a patient with ulcerative colitis.
Main Methods:
- A case report of a 31-year-old female with ulcerative colitis and oral PG.
- Treatment involved adalimumab, total colectomy, and microvascularized forearm flap reconstruction.
- A multidisciplinary approach was employed.
Main Results:
- Aggressive oral PG lesions necessitated total colectomy.
- The patient achieved a seven-year recurrence-free follow-up after surgical intervention.
- Comprehensive management led to successful disease control.
Conclusions:
- Severe pyoderma gangrenosum requires individualized, multidisciplinary management.
- Surgical intervention can be effective in refractory cases of oral PG.
- This case underscores the importance of a combined approach for complex PG presentations.
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