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Oral Vitamin B12 Versus Intra-Nasal Vitamin B12 in Transient Neurosensory Disturbances Following Third Molar Surgery:
Jayanthi Lingaraj1, D Prabhu Shankar2, Anantanarayanan Parameswaran2
1Meenakshi Cleft and Craniofacial Centre, Chennai, Tamil Nadu India.
Purpose:
The aim was to evaluate the clinical efficacy of intra-nasal vitamin B12 spray compared to oral B12 in the recovery of transient neurosensory disturbances of the lingual nerve post-mandibular third molar surgery.
Methods:
Thirty patients, who experienced paresthesia of the tongue a day after mandibular third molar surgery, participated in this study. They were randomly divided into two groups: Group 1 (intra-nasal vitamin B12 spray) and Group 2 (oral vitamin B12). Clinical neurosensory tests were conducted at various intervals, and the Fisher's exact test was performed for group comparisons based on recovery.
Results:
Out of the 30 patients (18 females and 12 males) with transient lingual neurosensory disturbances, after third molar extraction, 15 used the intra-nasal vitamin B12 spray, while the other 15 took oral vitamin B12 tablets. Significant recovery was observed in the nasal group compared to the oral group at POD 16 (p = 0.005) and POD 24 (p = 0.003)."
Conclusion:
Intra-nasal vitamin B12 sprays were found to be conducive adjuvants to treat transient neurosensory disturbances following third molar surgery. Further studies on its routine application post-neurosensory complications are recommended.

