Related Experiment Video

Updated: May 29, 2025

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
11:22

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Published on: October 15, 2019

27.7K

Identification of Two Novel Alleles HLA-B*14:136 and HLA-B*58:159 by Next-Generation Sequencing

Qingdong Guan1,2,3, Kristin Jacobson1, Aggie Gentile1

  • 1Manitoba Blood and Marrow Transplant Program, CancerCare Manitoba, Manitoba, Canada.

HLA
|February 4, 2025
PubMed

Abstract:

Two novel HLA-B alleles, HLA-B*14:136 and -B*58:159, identified by NGS during the routine HLA typing.

More Related Videos

Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation
08:07

Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation

Published on: September 6, 2017

10.0K
T and B Cell Receptor Immune Repertoire Analysis using Next-generation Sequencing
08:59

T and B Cell Receptor Immune Repertoire Analysis using Next-generation Sequencing

Published on: January 12, 2021

8.1K

Related Experiment Videos

Last Updated: May 29, 2025

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
11:22

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Published on: October 15, 2019

27.7K
Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation
08:07

Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation

Published on: September 6, 2017

10.0K
T and B Cell Receptor Immune Repertoire Analysis using Next-generation Sequencing
08:59

T and B Cell Receptor Immune Repertoire Analysis using Next-generation Sequencing

Published on: January 12, 2021

8.1K

Related Concept Videos

Next-generation Sequencing03:00

Next-generation Sequencing

87.2K
The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features....
87.2K
Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

12.4K
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
12.4K

Articles linked to this work by shared authors, journal, and citation graph.

Identification of the Novel HLA-B*27:03:01:02 Allele, and Confirmation of HLA-C*07:02:01:79 by NGS.

HLA·2026

Pediatric Heart Rate Variability During Play and Neurocognitive Testing: The Influence of Parental Attitudes Towards Play.

Developmental psychobiology·2025

Interactions between Gut Microbiota and Immunomodulatory Cells in Rheumatoid Arthritis.

Mediators of inflammation·2020

Manufacturing autologous myoblast for regenerative medicine applications.

Cytotechnology·2020

A Comprehensive Review and Update on the Pathogenesis of Inflammatory Bowel Disease.

Journal of immunology research·2019

Assessing Depression Following Injury or Illness: Preliminary Validation of the Neuropsychology.Org Measures of Anxiety and Depression (NOMAD) Scale.

PM & R : the journal of injury, function, and rehabilitation·2019

Characterisation of the Novel HLA-DQB1*03:612 Allele by Sequencing-Based Typing.

HLA·2026

Identification of a New HLA-DRB5 Allele in a Chinese Han Individual, HLA-DRB5*01:01:17.

HLA·2026

The Novel HLA-DQA1*03:02:06 Allele was Identified by Next-Generation Sequencing.

HLA·2026

The Novel HLA-DPB1*1903:01 Allele Was Likely Generated by a Recombination Event.

HLA·2026

Identification of the Novel HLA-DQB1*02:281 Allele by Third-Generation Sequencing.

HLA·2026

Characterisation of the Novel HLA-C*16:01:53 Allele by Next-Generation Sequencing.

HLA·2026

CRISPR-Cas9 genome editing: technological advances, delivery strategies and precision engineering of primary cells for therapeutic application in genetic disorders and diabetes mellitus.

Molecular biology reports·2026

Diversity at the HYP1 locus in potato cyst nematodes does not result from developmentally-programmed somatic mutations.

PloS one·2026

Interference of Competing Beneficial Mutations on Recombining Chromosomes.

Biology·2026

The shared evolutionary capacities of plasmids and extrachromosomal DNA.

Nature reviews. Genetics·2026

Hologenomic interactions promote the higher-order evolvability of phenotypic complexity.

Trends in genetics : TIG·2026

Targeted insertion of an optimized donor DNA is effective in a humanized mouse model of dominant retinitis pigmentosa.

Cell reports. Medicine·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us