Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

5.6K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
5.6K
Negative and Cognitive Symptoms of Schizophrenia01:30

Negative and Cognitive Symptoms of Schizophrenia

40
Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
40
Learning Disabilities01:25

Learning Disabilities

83
Learning disabilities are cognitive disorders caused by neurological impairments that affect cognitive functions like language and reading, without indicating overall intellectual or developmental challenges. These disabilities differ from global intellectual or developmental disabilities as they are limited to distinct cognitive functions. Common learning disabilities include dysgraphia, dyslexia, and dyscalculia, each of which impacts unique aspects of learning.
Dyslexia
Dyslexia is a...
83
Visual Agnosia01:12

Visual Agnosia

174
Visual agnosia is a condition characterized by the inability to recognize visually presented objects despite having normal vision. For instance, a person with visual agnosia can describe the shape and color of an object but cannot identify or name it. This impairment does not affect their visual field, acuity, color vision, brightness discrimination, language, or memory. An example of this condition in a social setting is someone at a dinner party asking for "that silver thing with a round...
174
Pulse amplitude and quality01:17

Pulse amplitude and quality

1.6K
Pulse amplitude is a crucial indicator of cardiac health because it provides valuable insights into the strength of left ventricular contractions and the overall uniformity of blood circulation within the vasculature. The strength of the pulse is directly related to the force with which the heart contracts and the volume of blood being pumped.
A weak or absent pulse may indicate reduced cardiac output or poor left ventricular contraction, which can be signs of cardiovascular dysfunction or...
1.6K
Subconsciousness and No Awareness01:15

Subconsciousness and No Awareness

227
The concept of subconscious awareness refers to the processing of information below the level of conscious thought, which significantly influences both behaviors and decisions. It is also known as waking subconscious awareness. This complex level of cognition operates without the direct awareness of the individual, facilitating rapid and simultaneous handling of multiple information streams.
An illustrative example of subconscious processing is its role in problem-solving. Often, individuals...
227

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Müller Cell Changes and Subretinal Membrane Formation in an Eye With Multifocal Geographic Atrophy.

Investigative ophthalmology & visual science·2026
Same author

Histologic Photoreceptor and Retinal Pigment Epithelium Degeneration in an Eye With Clinically Documented Geographic Atrophy of AMD.

Investigative ophthalmology & visual science·2026
Same author

Bilateral Retinocytoma with Germline RB1 Variant on Multimodal Imaging.

Ophthalmology. Retina·2026
Same author

Choroidal Vascular Findings in a Case of Multifocal Geographic Atrophy: A Clinicopathologic Correlation.

Investigative ophthalmology & visual science·2026
Same author

Peripheral retinal lesions in highly myopic children: prevalence, types and biometric correlates.

The British journal of ophthalmology·2026
Same author

De novo and inherited dominant variants in U4 and U6 snRNA genes cause retinitis pigmentosa.

Nature genetics·2026
Same journal

Acute Paracentral Scotoma Following Cosmetic Penile Filler Injection.

Retinal cases & brief reports·2026
Same journal

Intravitreous Methotrexate and Rituximab for Bilateral Diffuse Uveal Melanocytic Proliferation (BDUMP).

Retinal cases & brief reports·2026
Same journal

Multimodal imaging of ASHH in a case of Scrub Typhus Retinopathy.

Retinal cases & brief reports·2026
Same journal

Pathogenic Variants in HGSNAT associated with Autosomal Recessive Retinitis Pigmentosa without Overt Sanfilippo Syndrome.

Retinal cases & brief reports·2026
Same journal

Macular Choroidal Neovascularization in Peripapillary Hyperreflective Ovoid Mass-Like Structures (PHOMS): case report.

Retinal cases & brief reports·2026
Same journal

Endogenous Streptococcus Anginosus Endophthalmitis: A Case Report and Review of the Literature.

Retinal cases & brief reports·2026
See all related articles

Related Experiment Video

Updated: May 29, 2025

A Standardized Obstacle Course for Assessment of Visual Function in Ultra Low Vision and Artificial Vision
09:29

A Standardized Obstacle Course for Assessment of Visual Function in Ultra Low Vision and Artificial Vision

Published on: February 11, 2014

13.0K

FUNCTIONAL DEFICITS ASSOCIATED WITH DARK WITHOUT PRESSURE.

Lucy V Cobbs1,2, Jacques Bijon1,2, K Bailey Freund1,2

  • 1Vitreous Retina Macula Consultants of New York, New York, New York; and.

Retinal Cases & Brief Reports
|February 4, 2025
PubMed
Summary
This summary is machine-generated.

Dark without pressure (DWP) can cause progressive vision loss and reduced retinal sensitivity, contrary to previous beliefs. This study highlights DWP

Keywords:
dark without pressurehigh-resolution optical coherence tomographymicroperimetrymultimodal imaging

More Related Videos

Driving Simulation in the Clinic: Testing Visual Exploratory Behavior in Daily Life Activities in Patients with Visual Field Defects
11:12

Driving Simulation in the Clinic: Testing Visual Exploratory Behavior in Daily Life Activities in Patients with Visual Field Defects

Published on: September 18, 2012

17.3K
Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss
07:12

Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss

Published on: April 11, 2025

284

Related Experiment Videos

Last Updated: May 29, 2025

A Standardized Obstacle Course for Assessment of Visual Function in Ultra Low Vision and Artificial Vision
09:29

A Standardized Obstacle Course for Assessment of Visual Function in Ultra Low Vision and Artificial Vision

Published on: February 11, 2014

13.0K
Driving Simulation in the Clinic: Testing Visual Exploratory Behavior in Daily Life Activities in Patients with Visual Field Defects
11:12

Driving Simulation in the Clinic: Testing Visual Exploratory Behavior in Daily Life Activities in Patients with Visual Field Defects

Published on: September 18, 2012

17.3K
Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss
07:12

Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss

Published on: April 11, 2025

284

Area of Science:

  • Ophthalmology
  • Retinal Imaging
  • Visual Electrophysiology

Background:

  • Dark without pressure (DWP) has been historically considered a benign retinal finding.
  • Previous literature suggests DWP does not cause functional visual deficits.

Purpose of the Study:

  • To describe a patient presenting with progressive visual symptoms.
  • To correlate these symptoms with reduced retinal sensitivity in areas of DWP.
  • To investigate the diagnostic capabilities of microperimetry versus standard visual field testing for DWP.

Main Methods:

  • Retrospective chart review of a single patient with progressive visual complaints.
  • Comprehensive ophthalmic examinations including multimodal imaging.
  • Analysis of optical coherence tomography (OCT), OCT-angiography, and microperimetry data.

Main Results:

  • A 23-year-old male reported progressive blurred vision in peripheral visual fields.
  • Multimodal imaging revealed characteristic features of DWP in corresponding retinal areas.
  • Microperimetry demonstrated significantly reduced retinal sensitivity in DWP areas, while Humphrey visual field (HVF) 24-2 testing remained normal.

Conclusions:

  • DWP is not always a benign finding and can be associated with progressive visual complaints.
  • Microperimetry is a more sensitive tool than HVF 24-2 testing for detecting functional deficits in DWP.
  • This case challenges the established understanding of DWP as a functionally silent retinal anomaly.