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Systolic time intervals before and after haemodialysis
Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress
|January 1, 1985
Summary
Hemodialysis alters patient hemodynamics, affecting heart rate and blood pressure. Ejection fraction (EF) changes depend on pre-dialysis EF, with decreases in higher EF patients and increases in lower EF patients.
Area of Science:
- Cardiology
- Nephrology
- Physiology
Background:
- Hemodialysis is a critical treatment for end-stage renal disease.
- Understanding hemodynamic changes during hemodialysis is essential for patient management.
- Noninvasive monitoring provides valuable insights into cardiac function during the procedure.
Purpose of the Study:
- To investigate hemodynamic alterations in patients undergoing hemodialysis.
- To assess changes in systolic time intervals and ejection fraction (EF).
- To correlate pre-dialysis EF with post-dialysis EF variations.
Main Methods:
- Noninvasive measurement of systolic time intervals in 107 hemodialysis patients.
- Monitoring of heart rate, blood pressure, and left ventricular ejection time.
- Analysis of pre-dialysis and post-dialysis ejection fraction (EF).
Main Results:
- Hemodialysis led to increased heart rate and pre-ejection period index.
- Systolic and diastolic blood pressure, left ventricular ejection time, and isovolumic contraction time decreased.
- Patients with pre-dialysis EF >55% showed a ~10% decrease in post-dialysis EF, while those with EF <55% had a ~5% increase.
- The most significant EF decrease occurred in patients with normal heart size, elevated Sokolow-Lyon Index (SLI), and repolarization disorders.
Conclusions:
- Hemodialysis induces significant hemodynamic changes, including altered cardiac function.
- Pre-dialysis ejection fraction is a key predictor of post-dialysis EF response.
- Patients with specific cardiac markers (normal heart size, high SLI, repolarization disorders) are at higher risk for adverse EF changes during hemodialysis.