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Asthma and Atopic Diseases in Children with Autism Spectrum Disorders

Khaled Saad1, Mohamed Ezzat2, Amira Elhoufey3,4

  • 1Department of Pediatrics, Faculty of Medicine, Assiut University, Assiut, Egypt.

Journal of Pharmacy & Bioallied Sciences
|February 10, 2025
PubMed

Insights

Autism spectrum disorder (ASD) and atopic diseases are common in children. This study found higher rates of allergic diseases, excluding food allergy, in Egyptian children with ASD compared to controls.

Area of Science:

  • Pediatric Health
  • Neurodevelopmental Disorders
  • Allergy and Immunology

Background:

  • Autism spectrum disorder (ASD) and atopic diseases affect many children globally, with increasing prevalence.
  • The exact reasons for the rising incidence of these conditions are not fully understood.
  • Both genetic and environmental factors are implicated in the development of ASD and atopic conditions.

Purpose of the Study:

  • To investigate the frequency of atopic diseases in Egyptian children diagnosed with ASD.
  • To compare the prevalence of allergic conditions in children with ASD versus typically developing controls.

Main Methods:

  • A survey adapted from the International Study of Asthma and Allergies in Childhood (ISAAC) was used.
  • The survey included 23 points related to atopic conditions.
  • Parents of children with ASD and control children completed the questionnaires.

Main Results:

  • The study included 150 children with ASD and 100 control children.
  • All types of allergic diseases, except for food allergy, were found to be significantly more prevalent in children with ASD.
  • This suggests a potential link between ASD and increased susceptibility to certain allergic conditions.

Conclusions:

  • Allergic diseases are multifactorial, influenced by genetics and environment.
  • The findings indicate a higher prevalence of allergic diseases in children with ASD, supporting an association.
  • Further research with larger cohorts is recommended to confirm and expand upon these results.
Abstract

Keywords:
Autismallergyasthmaatopic dermatitis

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