Related Experiment Video
Updated: May 28, 2025

Micro-Computed Tomography Analysis of the Knee in Aged Dunkin-Hartley Guinea Pigs after Intra Articular Injection
Published on: August 2, 2024
Validation of a Novel Landmark-guided Intra-articular Postero-medial Surgeon-administered Injection Technique
Nicolas S Piuzzi1, Andrew I Spitzer2, Jason Mussell3
1Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, OH, USA.
Background:
This study aimed to define an intra-articular surgeon-administered technique that may be comparable to ultrasound (US)-guided adductor canal block (ACB).
Methods:
Five cadaver lower limbs were examined. An anesthesiologist administered a US-guided ACB using 20 mL of dilute indocyanine dye. An orthopedic surgeon performed a medial parapatellar arthrotomy and introduced an 18-gauge needle 1-2 cm proximal to the palpated adductor tubercle angled posteromedially. Needle position and dye spread were fluoroscopically documented.
Results:
This technique consistently reached the infrapatellar branch of the saphenous nerve, nerve to the vastus medialis muscle, and posterior capsule, with minimal proximal dye spread.
Conclusions:
This technique may be an efficient complement to ACB or surgeon infiltration or an alternative to US-guided ACB when it is not available.

