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Updated: Aug 7, 2026

Autologous Microfractured and Purified Adipose Tissue for Arthroscopic Management of Osteochondral Lesions of the Talus
Published on: January 23, 2018
MICRO-FRAGMENTED ADIPOSE TISSUE IN THE KNEE OSTEOARTHRITIS UNDER LOCAL ANESTHESIA
Bruno Butturi Varone1, Henrique Fuller1, Daniel Perini1
1Universidade de Sao Paulo, Faculdade de Medicina, Hospital das Clinicas HC-FMUSP, Sao Paulo, SP, Brazil.
Objective:
To assess the feasibility of the entire micro fragmented adipose tissue knee injection procedure under local anesthesia. From the subcutaneous harvesting and microfragmentation process to the intrarticular knee injection.
Methods:
A patient with bilateral knee osteoarthritis underwent adipose tissue harvesting and bilateral intra-articular micro fragmented adipose tissue knee injection under local anesthesia. Patient-related outcomes were collected before the procedure, 12 months, and 24 months follow-up. Womac, Koos, and VAS were recorded.
Results:
The visual analog scale, KOOS questionnaire, and WOMAC score all improved in the 12- and 24-month follow-ups.
Conclusion:
Adipose tissue harvesting and micro fragmented adipose tissue knee injection are procedures that can be performed under local anesthesia and have good patient report outcomes.

