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GAPDH, β-Actin, and β-Tubulin Display Age-Dependent Protein Expression Changes in the Mouse Cortex during Development

Daniella Rodriguez1, Michelle Nguyen1, Tejas Devata1

  • 1Department of Neuroscience, School of Behavioral and Brain Sciences, The University of Texas at Dallas, Richardson, Texas, USA.

Developmental Neuroscience
|February 10, 2025
PubMed
Summary

Glyceraldehyde 3-phosphate dehydrogenase (GAPDH), β-actin, and β-tubulin show significant expression changes in the developing mouse cortex. These findings highlight the need for caution when using these proteins as reference controls in developmental studies.

Keywords:
Animal modelCerebral cortexDeveloping brainHousekeeping proteinsNeural developmentNeurodevelopmentTotal proteinWestern blotting

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