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Updated: May 28, 2025

A Murine Model of Hemodialysis Access-Related Hand Dysfunction
Published on: May 31, 2022
Breaking point: Case series of tendon ruptures in Hemodialysis patients
Muhammed Ehsan Nazeer1, Dr Askhar Haphiz2, Dr Muhammed Nazeer3
1Trauma and Orthopaedics, North Cumbria integrated care trust,, Cumberland Infirmary, Carlisle, England, UK.
Introduction:
Spontaneous tendon ruptures in end stage kidney disease patients have the potential to cause long- term morbidity, and timely intervention is required to prevent complications that can severely affect the functional status of the patient.
Case Presentation:
A series of six tendons (two triceps tendons and two bilateral patellar tendons) in three patients with ESKD undergoing hemodialysis is discussed in this case series. Patients were aged 61, 44 and 26 years, and on hemodialysis for 5, 10 and 5 years, respectively.
Conclusion:
End -stage kidney disease is associated with a multitude of physiological changes, and the musculoskeletal system is no exception to this. Spontaneous tendon rupture is a multifactorial complication of ESKD, with serious implications for mobility and quality of life. As a result, these patients require a multifaceted approach to ensure optimum results and an early return to activity. We report a series of 6 spontaneous tendon ruptures in 3 patients with ESKD at our institution. We would like to outline the methods of repair for each case and further attempt to assess biochemical parameters that may have contributed to the disease process.
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