In-Hospital Pulmonary Thromboembolism Development by Disease at Admission　- A Nationwide, Retrospective,...

Area of Science:

• Cardiology
• Pulmonology
• Healthcare Management

Background:

• In-hospital pulmonary thromboembolism (PE) is a critical concern, yet research on its risk factors is limited.
• Effective prevention strategies necessitate a deeper understanding of patient-specific risk profiles.

Purpose of the Study:

• To analyze the incidence and risk factors of in-hospital PE.
• To identify patient demographics and pre-existing conditions associated with higher PE risk.
• To evaluate the utilization of prophylactic measures for PE.

Main Methods:

• A retrospective analysis of the Medical Data Vision database from January 2017 to December 2021.
• Inclusion of over 4.6 million hospitalized patients, comparing those with and without in-hospital PE events.
• Focus on patient characteristics, admission diagnoses (heart failure, femoral fracture, pneumonia, stroke, cancer), and prophylactic procedures.

Main Results:

• The overall incidence of in-hospital PE was 20.6 per 1,000 person-years.
• Patients with heart failure (34.6) and femoral fracture (35.3) exhibited higher PE incidence rates.
• A history of venous thromboembolism (VTE) was a significant risk factor across all analyzed subgroups.

Conclusions:

• While overall in-hospital PE incidence is low, specific patient groups face elevated risks.
• Hospitalized patients with a history of VTE, heart failure, or femoral fracture require careful risk assessment.
• Integrating medical history and admission diagnosis into risk stratification is crucial for effective PE prevention.