[Effect of human immunoglobulins on mouse intestinal microflora in dysbacteriosis]

Human immunoglobulins, injected into mice subcutaneously after their irradiation or at the beginning of antibiotic therapy, protected the mucous membrane of the proximal section of the small intestine from the penetration of enterobacteria. The formation of the protective barrier was observed when immunoglobulin preparations with the titer of antibodies to Escherichia coli O14 between 1:16 and 1:256 was used. The preliminary exhaustion of immunoglobulin preparations with E. coli strain O14 led to the complete loss of their protective properties.