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Updated: May 28, 2025

Evaluating Regional Pulmonary Deposition using Patient-Specific 3D Printed Lung Models
Published on: November 11, 2020
Regional lung ventilation during supraglottic and subglottic jet ventilation: A randomized cross-over trial
Marita Windpassinger1, Michal Prusak2, Jana Gemeiner2
1Department of Anaesthesia, Intensive Care Medicine and Pain Medicine, Division of General Anaesthesia and Intensive Care Medicine, Medical University of Vienna, Vienna, Austria; OutcomeResearch Consortium®, Houston, TX, USA.
Subglottic jet ventilation, used in laryngotracheal surgery, improved oxygenation and dorsal lung ventilation compared to supraglottic jet ventilation. Both methods effectively eliminated carbon dioxide.
Area of Science:
- Anesthesiology
- Respiratory Physiology
- Surgical Ventilation
Background:
- Supraglottic and subglottic jet ventilation are utilized in laryngotracheal surgery.
- Supraglottic ventilation is hypothesized to offer superior ventilation and atelectasis prevention.
Purpose of the Study:
- To evaluate if supraglottic ventilation leads to more posterior ventilation distribution, indicating better dependent-lung ventilation.
- To assess if supraglottic ventilation enhances oxygenation and carbon dioxide elimination.
Main Methods:
- A randomized, cross-over trial was conducted in an operating room setting.
- Thirty patients undergoing elective micro-laryngotracheal surgery were included.
- Regional ventilation was assessed using electrical impedance tomography, alongside arterial blood gas analysis.
Main Results:
- No significant difference was found in the center of ventilation between supraglottic and subglottic jet ventilation.
- Supraglottic ventilation showed slightly increased ventromedial and decreased dorsal lung ventilation.
- Arterial oxygenation was significantly worse with supraglottic ventilation, while carbon dioxide elimination was similar, with a slight advantage for supraglottic.
Conclusions:
- The center of ventilation distribution was comparable between supraglottic and subglottic jet ventilation.
- Subglottic jet ventilation improved dorsal-dependent lung ventilation and provided superior arterial oxygenation.
- Both techniques achieved effective carbon dioxide elimination.
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