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Application of Deep Learning-Based Medical Image Segmentation via Orbital Computed Tomography
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Unsupervised cross-modality domain adaptation via source-domain labels guided contrastive learning for medical image
Wenshuang Chen1, Qi Ye1, Lihua Guo2
1School of Electronic and Information Engineering, South China University of Technology, Wushan Road 381, Guangzhou, Guangdong, 510641, China.
Medical & Biological Engineering & Computing
|February 12, 2025
Summary
This study introduces a novel unsupervised domain adaptation framework for cross-modality medical image segmentation. The method enhances segmentation accuracy by aligning image and feature distributions between domains, outperforming existing techniques.
Area of Science:
- Medical Imaging
- Computer Vision
- Machine Learning
Background:
- Unsupervised domain adaptation (UDA) is crucial for improving model performance on target domains using source domain knowledge.
- Medical image segmentation often faces challenges due to domain shifts across different modalities.
- Existing UDA methods struggle to effectively bridge the gap in medical image segmentation tasks.
Purpose of the Study:
- To propose a unified domain adaptation framework for cross-modality medical image segmentation.
- To enhance model robustness and alignment from both image and feature perspectives.
- To leverage source domain information for improved target domain segmentation without labeled target data.
Main Methods:
- Fine-tuning Fourier-based Contrastive Style Augmentation (FCSA) for robust image alignment.
- Designing Source-domain Labels Guided Contrastive Learning (SLGCL) for feature alignment.
- Incorporating a generative adversarial network for spatial and contextual consistency.
Main Results:
- The proposed framework achieves superior performance in cross-modality medical image segmentation.
- Demonstrated significant improvements over state-of-the-art UDA methods on a whole heart segmentation task.
- The novel approach effectively aligns image and feature distributions, enhancing segmentation accuracy.
Conclusions:
- The unified UDA framework offers a powerful solution for cross-modality medical image segmentation.
- The integration of FCSA and SLGCL effectively addresses domain shift challenges.
- This work represents a significant advancement in unsupervised domain adaptation for medical imaging.

