Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Focusing of Light in the Eye01:16

Focusing of Light in the Eye

2.2K
Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
2.2K
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

386
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
386

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Short-Term Effects of Low-Level Red-Light Therapy on Central Retinal Function: A Combined Pattern ERG and Photopic ERG Study.

Vision (Basel, Switzerland)·2026
Same author

Is Cold Atmospheric Plasma Selective for Breast Tumor Cells? A Systematic Review.

International journal of molecular sciences·2026
Same author

The Aberrometric Effect of Corneal Plus Power Ring Distribution on Axial Length Growth in Myopic Children Undergoing Orthokeratology Treatment.

Children (Basel, Switzerland)·2026
Same author

Association of MR-proANP Circulating Levels with Ischemic Stroke of Cardioembolic Etiology: A Systematic Review and Meta-Analysis.

Translational stroke research·2025
Same author

Use of direct oral anticoagulants in patients with stroke transferred for thrombectomy.

Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology·2025
Same author

Fast and Slow Response of the Accommodation System in Young and Incipient-Presbyope Adults During Sustained Reading Task.

Journal of clinical medicine·2025

Related Experiment Video

Updated: May 28, 2025

Author Spotlight: Advancements in Refractive Surgical Correction for Presbyopia and Exploring Postoperative Visual Acuity
05:46

Author Spotlight: Advancements in Refractive Surgical Correction for Presbyopia and Exploring Postoperative Visual Acuity

Published on: September 20, 2024

353

Peripheral Defocus in Orthokeratology Myopia Correction: Systematic Review and Meta-Analysis.

António Queirós1,2, Inês Pinheiro1, Paulo Fernandes1,2

  • 1Clinical and Experimental Optometry Research Lab (CEORLab), School of Science, University of Minho, 4710-057 Braga, Portugal.

Journal of Clinical Medicine
|February 13, 2025
PubMed
Summary

Orthokeratology lenses effectively induce myopic defocus in children and adolescents. This systematic review and meta-analysis suggests potential benefits for myopia control using these specialized lenses.

Keywords:
myopia progressionmyopic defocusorthokeratologyperipheral refraction

More Related Videos

Binocular Dynamic Visual Acuity in Eyeglass-Corrected Myopic Patients
07:06

Binocular Dynamic Visual Acuity in Eyeglass-Corrected Myopic Patients

Published on: March 29, 2022

2.5K
Corneal Confocal Microscopy: A Novel Non-invasive Technique to Quantify Small Fibre Pathology in Peripheral Neuropathies
11:29

Corneal Confocal Microscopy: A Novel Non-invasive Technique to Quantify Small Fibre Pathology in Peripheral Neuropathies

Published on: January 3, 2011

26.5K

Related Experiment Videos

Last Updated: May 28, 2025

Author Spotlight: Advancements in Refractive Surgical Correction for Presbyopia and Exploring Postoperative Visual Acuity
05:46

Author Spotlight: Advancements in Refractive Surgical Correction for Presbyopia and Exploring Postoperative Visual Acuity

Published on: September 20, 2024

353
Binocular Dynamic Visual Acuity in Eyeglass-Corrected Myopic Patients
07:06

Binocular Dynamic Visual Acuity in Eyeglass-Corrected Myopic Patients

Published on: March 29, 2022

2.5K
Corneal Confocal Microscopy: A Novel Non-invasive Technique to Quantify Small Fibre Pathology in Peripheral Neuropathies
11:29

Corneal Confocal Microscopy: A Novel Non-invasive Technique to Quantify Small Fibre Pathology in Peripheral Neuropathies

Published on: January 3, 2011

26.5K

Area of Science:

  • Ophthalmology
  • Optometry
  • Vision Science

Background:

  • Myopia is a growing global health concern, particularly in children and adolescents.
  • Peripheral defocus is a key factor influencing myopia progression.
  • Orthokeratology lenses offer a method to modify peripheral refractive error.

Purpose of the Study:

  • To systematically review and meta-analyze the effect of peripheral defocus induced by orthokeratology lenses (PDOK) on myopia control.
  • To assess the efficacy of PDOK in inducing myopic defocus at specific peripheral eccentricities.

Main Methods:

  • A comprehensive literature search was performed on PubMed and Web of Science.
  • Included studies were randomized controlled trials (RCTs) and cohort studies reporting peripheral refraction data.
  • Data analysis involved meta-analysis of spherical equivalent peripheral refraction at 30° eccentricity.

Main Results:

  • Nine studies (3 RCTs, 6 cohort) involving 259 participants were included.
  • Orthokeratology lenses consistently induced significant myopic defocus at 30° nasal and temporal eccentricities (average M = -2.67 D).
  • Longer treatment durations (up to one year) showed a trend towards greater induced myopic defocus compared to shorter durations.

Conclusions:

  • Orthokeratology lenses are effective in inducing myopic defocus at 30° eccentricity in pediatric populations.
  • The findings support the potential of PDOK as a myopia control strategy.
  • Further research may optimize treatment durations for enhanced myopia control outcomes.