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Development of GUI-based simple independent dose calculation software without DICOM data transfer for high-dose-rate
Yuha Kim1, Yang Sheng2, Chunhao Wang2
1Panther Creek High School, Cary, North Carolina, USA.
Journal of Contemporary Brachytherapy
|February 13, 2025
Summary
This study developed user-friendly software for independent dose calculation verification in high-dose-rate brachytherapy. The software ensures accuracy, meeting clinical guidelines for radiation therapy treatment plans.
Area of Science:
- Medical Physics
- Radiation Oncology
- Software Development
Background:
- Independent dose calculation verification is crucial for clinical treatment plans before radiation therapy administration.
- Existing verification methods may lack efficiency or broad system compatibility.
- High-dose-rate (HDR) brachytherapy requires precise and timely dose calculations.
Purpose of the Study:
- To develop and present an independent, user-friendly software for second check dose calculations in clinical HDR brachytherapy.
- To ensure the software meets established clinical guidelines and provides accurate dose verification.
Main Methods:
- Developed software using Python 3 on Google Colab, deployable on standard computers.
- Utilized AAPM TG-43 formalism and consensus dataset for dose calculations.
- Validated against a commercial treatment planning system (Varian Brachy-Vision) using 117 clinical HDR brachytherapy plans (gynecological and IORT cases).
Main Results:
- Software-calculated doses showed a mean discrepancy of -1% ±0.36% compared to the treatment planning system, well within the AAPM guideline (<5% deviation).
- The software's graphical user interface (GUI) simplifies input and operation, requiring no additional software or manual data entry.
- Demonstrated particular advantage for intra-operative radiation therapy (IORT) requiring rapid, offline verification.
Conclusions:
- A streamlined, executable GUI software for HDR brachytherapy dose verification was successfully developed using TG-43 formalism.
- The software is accurate, meets clinical practice guidelines, and is compatible with Windows, MacOS, and Linux systems.
- The software will be publicly available, enhancing accessibility for independent dose verification in radiation oncology.
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