Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Forced Transdifferentiation01:28

Forced Transdifferentiation

1.9K
Transdifferentiation, also known as lineage reprogramming, was first discovered by Selman and Kafatos in 1974 in silkmoths. They observed that the moths’ cuticle-producing cells transformed into salt-producing cells. Many such cases of natural transdifferentiation occur in organisms. In humans, pancreatic alpha cells can become beta cells. In newts, the loss of the eye’s lens causes the pigmented epithelial cells to transdifferentiate into the lens cells.
Artificial...
1.9K
Somatic to iPS Cell Reprogramming01:29

Somatic to iPS Cell Reprogramming

2.2K
Reprogramming alters the gene expression in somatic cells, transforming them into induced pluripotent stem (iPS) cells over several generations. Scientists can reprogram cells by introducing genes for four transcription factors—Oct4, Sox2, Klf4, and c-Myc (OSKM) by viral or non-viral methods. These factors are also known as Yamanaka factors after Shinya Yamanaka, who first generated iPS cells using mouse skin cells. Yamanaka was awarded the Nobel Prize in Physiology or Medicine in 2012...
2.2K
Introduction To Health Care Delivery System01:18

Introduction To Health Care Delivery System

2.6K
The healthcare system is constantly changing and complex. Various services are available from different healthcare providers, but gaining access to these services has become challenging for people with limited healthcare insurance. Uninsured people present a challenge to healthcare because they frequently postpone or forego treatment.
The Institute of Medicine (IOM) advocates for a patient-centered, effective, safe, timely, equitable, and effective healthcare system. The National Priorities...
2.6K
Methods of Documentation II: POMR01:26

Methods of Documentation II: POMR

902
The Problem-Oriented Medical Record (POMR) revolutionized medical record-keeping by introducing a systematic approach focusing on the patient's problems rather than merely listing symptoms. Dr. Lawrence Weed's introduction of this method in the 1960s marked a significant advancement in medical documentation. The POMR framework consists of four key components: the database, problem list, plan of care, and progress notes.
902
Primary Healthcare Services01:30

Primary Healthcare Services

1.3K
Primary care promotes wellness and prevents disease. This care includes health promotion, education, protection (such as immunizations), early disease screening, and environmental considerations. Settings providing this type of healthcare include physician offices, public health clinics, school nursing, and community health nursing.
In 1978, international leaders convened in Alma-Ata, Kazakhstan, for what would be a pivotal event in global health. The Alma-Ata Declaration was the first to call...
1.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Jump-starting the T cell response in established tumors.

bioRxiv : the preprint server for biology·2026
Same author

Multiple incomplete surgical and procedural interventions correlate with hyperprogression of a pleomorphic dermal sarcoma - a case report.

Journal of surgical case reports·2026
Same author

Protocol for incomplete murine tumor resection to study local effects of surgical trauma on residual sarcoma.

STAR protocols·2026
Same author

Rapid Isolation of Human Breast Milk-Derived Extracellular Vesicles.

Journal of visualized experiments : JoVE·2025
Same author

Dedicated review of sarcoma pathology is necessary for corroborative diagnosis in nearly one half of referred patients.

Surgery·2025
Same author

Maternal Quality of Life Following a Periviable Delivery.

Ochsner journal·2025

Related Experiment Video

Updated: May 27, 2025

Improving Student Outcomes with an Adaptable Molecular Cloning Course-Based Undergraduate Research Experience
10:17

Improving Student Outcomes with an Adaptable Molecular Cloning Course-Based Undergraduate Research Experience

Published on: November 15, 2024

925

Paradigm shift: outcomes from a physician-scientist undergraduate pathway program.

Alana C Jones1, Tyler R McCaw2, Randy L Seay3

  • 1Medical Scientist Training Program, University of Alabama at Birmingham, Birmingham, AL, USA.

BMC Medical Education
|February 15, 2025
PubMed
Summary

The PARAdiGM program successfully increases entry of underrepresented in medicine (URiM) students into physician-scientist training. Early results show most alumni attend medical school, with 12% in MD-PhD programs, indicating program effectiveness.

Keywords:
Biomedical researchPhysician-scientist diversityPhysician-scientist workforcePipeline program

More Related Videos

Bridging the Technology Divide in the COVID-19 Era: Using Virtual Outreach to Expose Middle and High School Students to Imaging Technology
09:55

Bridging the Technology Divide in the COVID-19 Era: Using Virtual Outreach to Expose Middle and High School Students to Imaging Technology

Published on: September 28, 2022

1.6K
A Web Tool for Generating High Quality Machine-readable Biological Pathways
08:01

A Web Tool for Generating High Quality Machine-readable Biological Pathways

Published on: February 8, 2017

17.5K

Related Experiment Videos

Last Updated: May 27, 2025

Improving Student Outcomes with an Adaptable Molecular Cloning Course-Based Undergraduate Research Experience
10:17

Improving Student Outcomes with an Adaptable Molecular Cloning Course-Based Undergraduate Research Experience

Published on: November 15, 2024

925
Bridging the Technology Divide in the COVID-19 Era: Using Virtual Outreach to Expose Middle and High School Students to Imaging Technology
09:55

Bridging the Technology Divide in the COVID-19 Era: Using Virtual Outreach to Expose Middle and High School Students to Imaging Technology

Published on: September 28, 2022

1.6K
A Web Tool for Generating High Quality Machine-readable Biological Pathways
08:01

A Web Tool for Generating High Quality Machine-readable Biological Pathways

Published on: February 8, 2017

17.5K

Area of Science:

  • Medical Education
  • Academic Medicine
  • Physician-Scientist Training

Background:

  • Physician-scientists bridge research and clinical practice.
  • Underrepresented in medicine (URiM) trainees face barriers in physician-scientist pathways.
  • Structural inequities limit diversity in academic medicine.

Purpose of the Study:

  • To introduce students from underrepresented and disadvantaged backgrounds to physician-scientist training.
  • To provide early exposure, mentorship, and support for URiM students.
  • To prime students for careers in academic medicine.

Main Methods:

  • The Preparation for Graduate and Medical Education (PARAdiGM) program offers early exposure to physician-scientist training.
  • Emphasis on research experience, career exposure, presentation skills, and mentorship.
  • Programmatic support and application assistance for students.

Main Results:

  • PARAdiGM increases URiM student entry into the physician-scientist pathway.
  • Most PARAdiGM alumni matriculate into US medical schools.
  • 12% of PARAdiGM alumni are enrolled in MD-PhD programs.

Conclusions:

  • Immersive frameworks, longitudinal mentoring, and self-growth opportunities are crucial for URiM pathway programs.
  • PARAdiGM's success suggests a scalable model for increasing URiM physician-scientists.
  • Supporting URiM students' self-perception as scientists can dismantle barriers in academic medicine.