Multiple Myxoid Meningiomas Exhibiting Rapid Growth: A Case Report and Literature Review

Myxoid meningioma is an extremely rare subtype of metaplastic meningioma, with only 17 cases reported in the literature. We present the case of an 85-year-old male who was diagnosed with multiple brain tumors following a magnetic resonance imaging scan that was performed because of progressive cognitive decline and aphasia for over 1 month. The tumors were located in the left anterior cranial fossa, left middle cranial fossa, and along the left sphenoid ridge. Gross total resection was performed on the tumors in the sphenoid ridge and middle cranial fossa. Histopathological examination confirmed the diagnosis of myxoid meningioma, although necrosis and increased cellular density suggested the possibility of an atypical meningioma. This is the first reported case of multiple lesions in a myxoid meningioma. Although myxoid meningiomas are classified as World Health Organization grade 1, their potential for rapid growth and clinically aggressive behavior warrant careful attention.