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Related Experiment Video

Updated: May 15, 2026

Multi-Scale Modification of Metallic Implants With Pore Gradients, Polyelectrolytes and Their Indirect Monitoring In vivo
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Reconstructive Peri-implant Site Development Throughout an Implant Life Cycle: A Retrospective Study.

Khushboo Kalani, Sandra Stuhr, Abdusalam Alrmali

    The International Journal of Oral & Maxillofacial Implants
    |February 19, 2025
    PubMed
    Summary

    Regenerative procedures (ReP) are common in dental implant therapy, with nearly half of patients undergoing them. Diabetics require more ReP, and these augmentations represent a significant portion of overall implant costs.

    Keywords:
    alveolar ridge augmentationcost analysisdental implantsprevalenceregeneration

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    Area of Science:

    • Dental implantology
    • Regenerative medicine
    • Periodontology

    Background:

    • Regenerative procedures (ReP) are essential for successful dental implant therapy, involving hard and soft tissue augmentation.
    • Understanding the frequency, timing, and financial impact of ReP is crucial for patient management and treatment planning.

    Purpose of the Study:

    • To evaluate the incidence, timing, and cost of regenerative procedures (ReP) in dental implant therapy.
    • To investigate the influence of systemic conditions on the need for additional regenerative interventions.
    • To analyze the types of ReP performed and their anatomical distribution.

    Main Methods:

    • A retrospective cohort study of 4,803 patients who received implants between 2011-2023.
    • Data collected included patient demographics, systemic health conditions, and details of regenerative procedures.
    • Univariable and multivariable logistic regression analyses were used to identify factors influencing ReP.

    Main Results:

    • Nearly half of patients (48.9%) and over a fifth of implants (21.7%) received at least one ReP.
    • Alveolar ridge augmentation (ARA) and alveolar ridge preservation (ARP) were the most common ReP.
    • Diabetic patients showed significantly higher odds of needing ReP both before and after implant placement.

    Conclusions:

    • Regenerative procedures are frequently utilized in dental implant cases, with ARA and ARP being prevalent.
    • Systemic conditions, particularly diabetes, significantly increase the likelihood of requiring regenerative interventions.
    • Regenerative procedures constitute a notable cost in implant therapy, highlighting the need for efficient treatment strategies.