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Digital Solution to Support Medication Adherence and Self-Management in Patients with Cancer (SAMSON): Pilot

Thu Ha Dang1,2,3, Nilmini Wickramasinghe4,5,6, Prem Prakash Jayaraman7

  • 1Department of Psychological Sciences, School of Health Sciences, Swinburne University of Technology, Melbourne, Australia.

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Summary

The digital Safety and Adherence to Medications and Self-care Advice in Oncology (SAMSON) solution demonstrated high acceptability and feasibility in a pilot study for cancer patients, supporting medication adherence and self-management.

Keywords:
RCTSAMSONcancerdigital solutioneHealthhome-based cancer treatmentmHealthmedication adherencemobile healthmobile phoneoncologyoral chemotherapypatient safetypilot studyquality of liferandomized controlled trialself-managementsmartphone app

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Area of Science:

  • Digital health interventions in oncology
  • Medication adherence and self-management support

Background:

  • Medication nonadherence is a significant challenge in cancer care, impacting patient outcomes and healthcare costs.
  • Existing technology-based interventions for medication adherence (MA) have limited evidence of quality and effectiveness.

Purpose of the Study:

  • To evaluate the acceptability, feasibility, and potential effects of the SAMSON digital solution for supporting MA and self-management in cancer patients.
  • To assess patient and healthcare professional (HCP) perceptions of the SAMSON solution.

Main Methods:

  • A 12-week, pragmatic pilot randomized controlled trial involving adults with hematological malignancies.
  • The SAMSON intervention included a smartphone app, HCP dashboard, and motivational interviewing (MI) teleconsultations.
  • Outcomes included technology acceptance, study feasibility, MA, self-management, and quality of life.

Main Results:

  • High patient acceptability (87% app usage, 93% MI delivery) and perceived usefulness for MA (50%).
  • Feasibility metrics exceeded predefined thresholds, with high completion rates for consultations and tasks.
  • Patients rated SAMSON as easy to use (83%), and HCPs found it helpful for supporting MA.

Conclusions:

  • The SAMSON solution is acceptable, usable, and feasible for patients and HCPs in oncology settings.
  • Further refinement and a large-scale trial are planned to assess clinical and economic effectiveness.
  • Potential commercialization of the SAMSON solution is being explored.