Conduction System Pacing-Optimized Cardiac Resynchronization Therapy for Congenitally Corrected Transposition
Jonathan Su1, Wilson W Lam2, Anisha Contractor1
1Department of Pediatrics, University of California-Los Angeles (UCLA), Los Angeles, California, USA.
JACC. Case Reports
|February 20, 2025
Summary
Congenitally corrected transposition of the great arteries (CCTGA) patients with RV electrical delay may benefit from conduction system pacing-optimized cardiac resynchronization therapy (CRT). This approach improved electrical synchrony and clinical outcomes in three cases.
Area of Science:
- Cardiology
- Electrophysiology
- Congenital Heart Disease
Background:
- Congenitally corrected transposition of the great arteries (CCTGA) patients face risks of atrioventricular block, pacing-induced cardiomyopathy, and right ventricular (RV) failure.
- Existing treatments like biventricular cardiac resynchronization therapy (CRT) and conduction system pacing (CSP) may not fully resolve RV failure in these complex cases.
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