Related Experiment Video
Updated: May 27, 2025

09:47
Author Spotlight: Utilizing Next-Generation Polymerized Human Hemoglobin for Improved Donor Lung Evaluation and Preservation in Rats
Published on: June 14, 2024
471
Parallel Venvovenous Extracorporeal Membrane Oxygenation Circuits During Bridge-to-Lung Transplantation
Donias Doko1, Christina Creel-Bulos2,3,4, Keely Collins5
1From the Department of Anesthesiology, Emory University School of Medicine, Atlanta, Georgia.
Summary
This case study shows how parallel extracorporeal membrane oxygenation (ECMO) circuits can support patients with severe respiratory failure, enabling physical therapy (PT) and facilitating lung transplant. This approach bridges patients to recovery and hospital discharge.
Area of Science:
- Critical Care Medicine
- Cardiopulmonary Support
- Rehabilitation Medicine
Background:
- Venovenous extracorporeal membrane oxygenation (VV ECMO) is a life-support technology for severe respiratory failure.
- Physical therapy (PT) on VV ECMO offers potential benefits for strength and conditioning.
- Maintaining pulmonary reserve is crucial for patients awaiting lung transplant or recovery.
Purpose of the Study:
- To report a case of successful VV ECMO support using parallel, independent circuits.
- To demonstrate the feasibility of continuing PT in a complex ECMO case.
- To highlight bridging to lung transplant and hospital discharge.
Main Methods:
- The patient required VV ECMO due to refractory respiratory failure, complicated by cardiac arrest and cardiogenic shock.
- Parallel, independent VV ECMO circuits were implemented for enhanced support.
- Physical therapy was continued throughout the ECMO support period.
Main Results:
- The parallel VV ECMO configuration successfully managed the patient's critical condition.
- Ongoing PT contributed to maintaining functional status during ECMO support.
- The patient successfully bridged to lung transplantation, was decannulated, and discharged from the hospital.
Conclusions:
- Parallel, independent VV ECMO circuits can provide robust support in complex cases.
- Integrating physical therapy with advanced ECMO support is feasible and beneficial.
- This strategy can improve outcomes for patients with refractory respiratory failure awaiting lung transplantation.

