Machine learning or traditional statistical methods for predictive modelling in perioperative medicine: A narrative
Jason Mann1, Mathew Lyons2, John O'Rourke3
1Sheffield Teaching Hospitals NHS Foundation Trust, Royal Hallamshire Hospital, Anaesthesia and Operating Services, C-floor, Glossop Road, Sheffield, South Yorkshire S11 2JF, UK.
Journal of Clinical Anesthesia
|February 20, 2025
Summary
Machine learning (ML) shows promise in improving perioperative outcome prediction models, but benefits are context-dependent. High-quality reporting and interpretability are crucial for clinical integration of ML in medicine.
Area of Science:
- Perioperative Medicine
- Medical Informatics
- Machine Learning Applications
Background:
- Accurate prediction of perioperative outcomes is essential for clinical decision-making and risk communication.
- Machine learning (ML) is increasingly explored for enhancing predictive accuracy compared to traditional statistical models.
- Concerns exist regarding the quality of ML studies and the clinical meaningfulness of performance gains.
Purpose of the Study:
- To review and appraise studies developing perioperative predictive ML models.
- To compare the predictive performance of ML models against traditional statistical models.
- To identify factors influencing the successful application of ML in perioperative prediction.
Main Methods:
- A narrative review was conducted due to heterogeneity in study populations and outcomes.
- Data were extracted from 37 studies identified through systematic search, screening, and full-text review.
- Studies focused on the development and validation of perioperative predictive models.
Main Results:
- Several studies demonstrate that ML can enhance perioperative prediction models.
- The performance improvement offered by ML is not universal and remains context-dependent.
- Traditional statistical models also continue to be developed and show relevant performance.
Conclusions:
- ML models show potential to augment traditional methods for perioperative outcome prediction.
- Clinical utility depends on factors like patient-centered outcomes, interpretability, and external validation.
- High standards in reporting and methodological transparency are vital for advancing ML in clinical practice.
Related Concept Videos
Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving
38
Mechanistic models play a crucial role in algorithms for numerical problem-solving, particularly in nonlinear mixed effects modeling (NMEM). These models aim to minimize specific objective functions by evaluating various parameter estimates, leading to the development of systematic algorithms. In some cases, linearization techniques approximate the model using linear equations.
In individual population analyses, different algorithms are employed, such as Cauchy's method, which uses a...
In individual population analyses, different algorithms are employed, such as Cauchy's method, which uses a...
38
Kaplan-Meier Approach
78
The Kaplan-Meier estimator is a non-parametric method used to estimate the survival function from time-to-event data. In medical research, it is frequently employed to measure the proportion of patients surviving for a certain period after treatment. This estimator is fundamental in analyzing time-to-event data, making it indispensable in clinical trials, epidemiological studies, and reliability engineering. By estimating survival probabilities, researchers can evaluate treatment effectiveness,...
78


