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Updated: May 26, 2025

An Experimental Paradigm for the Prediction of Post-Operative Pain PPOP
Published on: January 27, 2010
Patients' experiences with pain and bleeding in first-trimester abortion care
Katherine M Mahoney1, Rachel McKean2, Arden McAllister2
1Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
Patients undergoing medication abortion, especially those with a history of severe menstrual pain or depression, are more likely to report severe pain and heavy bleeding. Anticipatory guidance can improve the abortion experience by addressing these risk factors.
Area of Science:
- Reproductive Health
- Clinical Obstetrics and Gynecology
- Patient-Reported Outcomes
Background:
- Abortion care is a common and safe medical procedure.
- Patient experience of pain and bleeding significantly impacts satisfaction.
- Limited research exists on factors influencing severe pain and bleeding in contemporary abortion methods.
Purpose of the Study:
- To identify clinical predictors of severe pain and heavy bleeding reported by patients undergoing first-trimester abortions.
- To analyze factors associated with the discrepancy between expected and experienced pain and bleeding.
Main Methods:
- Secondary analysis of a multicenter prospective cohort study.
- Included 644 participants undergoing medication or procedural abortion up to 11 weeks 6 days gestation.
- Logistic regression models assessed predictors of severe pain, heavy bleeding, and discordance between expected and experienced symptoms.
Main Results:
- One-fourth of participants reported severe pain; 35% reported heavy bleeding.
- Medication abortion, history of severe menstrual pain, and baseline depression predicted severe pain.
- Medication abortion regimen and baseline depression predicted heavy bleeding.
- First abortion experience, nulliparity, prior cesarean delivery, and baseline depression predicted pain discordance.
Conclusions:
- While most patients are prepared for abortion-related symptoms, severe pain and heavy bleeding are significant concerns for some.
- Identifying patients with risk factors for severe pain and heavy bleeding can guide anticipatory counseling.
- Improved anticipatory guidance incorporating identified risk factors may enhance the overall patient experience.
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