Related Experiment Video
Updated: May 26, 2025
06:08
Pulse Wave Velocity Testing in the Baltimore Longitudinal Study of Aging
Published on: February 7, 2014
17.0K
Assessing the Validity of Computerized Algorithms for Determining Pulse Wave Velocity: A Clinical Study
Amira Tairi1, Hasan Obeid2, Saliha Addour2
1Division of Nephrology, Department of Medicine, CHU de Québec-Université Laval Research Center, Faculty of Medicine, Université Laval, Québec City, QC, Canada.
Pulse (Basel, Switzerland)
|February 24, 2025
Summary
The study found that the second-derivative and intersecting tangents algorithms for calculating pulse wave velocity (PWV) yield negligible differences in results. This suggests no need to adjust PWV measurements based on the algorithm used for pulse transit time determination.
Area of Science:
- Cardiovascular Physiology
- Biomedical Engineering
- Medical Diagnostics
Background:
- Aortic stiffness, measured by carotid-femoral pulse wave velocity (PWV), is a key cardiovascular risk factor.
- Accurate PWV measurement relies on precise identification of the pulse waveform foot.
- Existing methods, such as second-derivative and intersecting tangents algorithms, can produce differing PWV results.
Purpose of the Study:
- To compare pulse transit time (PTT) and PWV calculated by second-derivative and intersecting tangents algorithms.
- To evaluate differences when both algorithms process identical input signals.
Main Methods:
- Analyzed 3,770 pairs of filtered pulse waves from 113 subjects using MATLAB.
- Calculated PTT and PWV with second-derivative (PTTMat-2nd, PWVMat-2nd) and intersecting tangents (PTTMat-IT, PWVMat-IT) algorithms.
- Compared results with Complior (PWVComp-2nd) and SphygmoCor (PWVSphyg-IT) systems.
Main Results:
- Mean PTT values were nearly identical: 54.55 ± 18.55 ms (2nd derivative) vs. 54.61 ± 18.61 ms (intersecting tangents).
- Mean PWV values showed minimal differences: 0.01 ± 0.32 m/s between MATLAB algorithms (PWVMat-2nd vs. PWVMat-IT).
- Differences between device-specific algorithms were also small: 0.11 ± 0.66 m/s (PWVComp-2nd vs. PWVSphyg-IT).
Conclusions:
- The differences in PWV calculated by the second-derivative and intersecting tangents algorithms are negligible.
- No adjustment is needed for PWV measurements based on the algorithm used for PTT determination.
- This finding simplifies the interpretation of PWV measurements across different analytical approaches.
Related Concept Videos
01:13Special considerations while measuring pulse
551
Assessing a patient's pulse is a fundamental skill in healthcare, but certain situations require special attention:
551
01:19Assessing Blood pressure using a doppler ultrasound
1.2K
To obtain accurate blood pressure measurements in clinical settings, especially when traditional methods are insufficient, healthcare professionals utilize the Doppler ultrasound technique. This method uses high-frequency sound waves to detect blood flow within the arteries, which is crucial for patients with conditions that complicate circulatory system assessment.
Pre-Procedural Guidelines for Doppler Ultrasound Blood Pressure Assessment:
Preparation of Equipment:
Pre-Procedural Guidelines for Doppler Ultrasound Blood Pressure Assessment:
Preparation of Equipment:
1.2K
01:16Pulse
417
When the heart pumps blood out, arterial elastic fibers play a crucial role in sustaining a high-pressure gradient. They expand to accommodate the received blood and then recoil - a process known as the pulse that can be either manually palpated or electronically quantified. Despite a reduction in its effect with increased distance from the heart, elements of the pulse's systolic and diastolic components persist, observable even at the arteriole level.
The pulse serves as a clinical...
The pulse serves as a clinical...
417
01:23Assessment of blood pressure in brachial artery(two-step method)
644
Measuring blood pressure is a fundamental skill in healthcare that aids in diagnosing and monitoring hypertension and other cardiovascular conditions. An aneroid sphygmomanometer, commonly used in clinical settings, offers a manual and precise method for blood pressure measurement. The technique for using this instrument involves specific steps that must be carefully executed to ensure accuracy. The following detailed description outlines a two-step technique for assessing blood pressure using...
644
01:17Pulse amplitude and quality
1.6K
Pulse amplitude is a crucial indicator of cardiac health because it provides valuable insights into the strength of left ventricular contractions and the overall uniformity of blood circulation within the vasculature. The strength of the pulse is directly related to the force with which the heart contracts and the volume of blood being pumped.
A weak or absent pulse may indicate reduced cardiac output or poor left ventricular contraction, which can be signs of cardiovascular dysfunction or...
A weak or absent pulse may indicate reduced cardiac output or poor left ventricular contraction, which can be signs of cardiovascular dysfunction or...
1.6K
01:10Pre-Procedural Guidelines for Assessing Blood Pressure
518
Accurate blood pressure assessment is crucial for diagnosing and managing various health conditions. To ensure the reliability of these measurements, healthcare professionals must adhere to standardized pre-procedural guidelines. These guidelines enhance patient safety and improve the overall quality of healthcare. The following steps are essential for obtaining accurate and consistent blood pressure readings, from using the appropriate tools to ensuring effective communication with the...
518