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MRpoxNet: An enhanced deep learning approach for early detection of monkeypox using modified ResNet50
Vandana1, Chetna Sharma1, Mohd Asif Shah2,3,4
1Chitkara University Institute of Engineering and Technology, Chitkara University, Rajpura, India.
Digital Health
|February 27, 2025
Summary
A new deep learning model, MRpoxNet, accurately detects monkeypox from skin images. This advanced AI tool shows high diagnostic accuracy for early monkeypox identification.
Area of Science:
- Medical Imaging
- Artificial Intelligence
- Dermatology
Background:
- Early detection of monkeypox is crucial for effective public health response.
- Digital imaging offers a non-invasive method for diagnosing skin conditions.
- Deep learning models show promise in analyzing medical images for disease identification.
Purpose of the Study:
- To develop an enhanced deep learning model, MRpoxNet, for early monkeypox detection.
- To achieve high diagnostic accuracy and clinical reliability in identifying monkeypox from skin lesions.
- To leverage a modified ResNet50 architecture for improved performance.
Main Methods:
- Utilized an augmented dataset of 6116 skin lesion images (monkeypox, non-monkeypox, normal skin).
- Developed MRpoxNet by extending the ResNet50 architecture with additional layers.
- Evaluated performance using accuracy, precision, recall, F1 score, sensitivity, and specificity, comparing against established models.
Main Results:
- MRpoxNet achieved a diagnostic accuracy of 98.1%, surpassing baseline models.
- The model demonstrated superior robustness in distinguishing monkeypox lesions.
- All key performance metrics indicated high diagnostic reliability.
Conclusions:
- MRpoxNet offers a robust and efficient solution for early monkeypox detection.
- The model's performance suggests its suitability for integration into clinical diagnostic workflows.
- Future work includes dataset expansion and multimodal adaptability for diverse clinical scenarios.

