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Related Experiment Video

Updated: May 24, 2025

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A Simple Circuit for Time-Resolved Luminescence (TRL) Measurement Instruments: Demonstration Through a

Alim Gulbag1, Michael Huang1, Brian Rong1

  • 1Department of Electrical and Biomedical Engineering, University of Nevada Reno, NV 98557 USA.

IEEE Sensors Letters
|March 3, 2025
PubMed
Summary

Researchers developed a simple circuit for compact time-resolved luminescence (TRL) imagers. This innovation enables low-cost, portable TRL instruments for point-of-care applications.

Keywords:
Time-resolved luminescenceanticounterfeitingoptical choppersmartphonesynchronization

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Area of Science:

  • Analytical Chemistry
  • Instrumentation Science

Background:

  • Time-resolved luminescence (TRL) measurement offers sensitive detection by minimizing autofluorescence.
  • Existing TRL instruments are often complex, costly, and bulky, hindering point-of-care and field use.

Purpose of the Study:

  • To develop a simplified, cost-effective circuit for rapid LED pulsing and precise timing synchronization.
  • To implement this circuit in a compact TRL imager for broader accessibility.

Main Methods:

  • Designed a novel circuit for rapid LED pulsing and accurate synchronization.
  • Integrated the circuit into a TRL imager utilizing a UV LED and a smartphone camera with a chopper.
  • Validated the TRL imager's performance using an anticounterfeiting application.

Main Results:

  • Successfully developed and implemented a simple, low-cost circuit for TRL instrumentation.
  • Demonstrated a compact TRL imager capable of sensitive measurements.
  • Validated the imager's effectiveness in a practical anticounterfeiting scenario.

Conclusions:

  • The developed circuit significantly reduces the cost and complexity of TRL instruments.
  • This advancement paves the way for compact, affordable TRL devices for point-of-care and in-field applications.
  • The technology holds potential for widespread adoption in various diagnostic and security fields.