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Updated: May 24, 2025

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Decoupling Activity and Specificity in Coronazymes.

Jiahao Ji1, Li Zuo1,2, Bishal Pokhrel1

  • 1Department of Chemistry & Biochemistry, Kent State University, Kent, OH, 44242, USA.

Small (Weinheim an Der Bergstrasse, Germany)
|March 4, 2025
PubMed
Summary

This study introduces novel coronazymes, artificial enzymes combining gold nanoparticles and DNA aptamers. These engineered enzymes show enhanced activity and tunable specificity, decoupling key properties for superior catalyst design.

Keywords:
CISSactivity and specificitychiral modulationmodular designmosaicking

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