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Photoinduced Assembly of Diverse Homoallylic Boronates from gem-Diborons
Tangfeng Yao1, Chenchen Zhao1, Chaokun Li1
1Key Laboratory of Molecule Synthesis and Function Discovery, Fujian Province University, College of Chemistry at Fuzhou University, Fuzhou, Fujian 350108, People's Republic of China.
Abstract:
In comparison to alkyl monoboron or 1,2-diboron, which can generate alkyl radicals via tetracoordinate boron species under photocatalytic conditions, the participation of gem-diborons as substrates in such reactions remains to be developed. Herein, we report a method utilizing gem-diborons as starting materials to generate α-boryl radicals, which then react with various olefins, successfully and efficiently constructing a diverse range of high-value homoallylic boronates; meanwhile, the gem-difluorohomoallylic skeletons could also be smoothly obtained. This transformation demonstrates broad substrate scope and excellent tolerance toward functional groups, enhancing the utility of gem-diboron as precursors for C-C bond construction and the production of valuable products.
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