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Demographics, Management, and Outcomes Associated With Idiopathic Vocal Fold Paralysis: A Systematic Review
Corinne Stonebraker1, Romy Pein1, Zachary A Valley1
1School of Medicine, New York Medical College, Valhalla, New York, USA.
Idiopathic vocal fold paralysis (IVFP) affects voice, breathing, and swallowing. Research shows unilateral paralysis is common, with a 31.6% spontaneous recovery rate, but causes remain unclear.
Area of Science:
- Otolaryngology
- Neurology
- Medical Research
Background:
- Idiopathic vocal fold paralysis (IVFP) presents significant challenges impacting voice, breathing, and swallowing.
- Understanding the demographics, management, and outcomes of IVFP is crucial for patient care.
Purpose of the Study:
- To systematically review and discuss the demographics, management, and outcomes of idiopathic vocal fold paralysis.
- To synthesize current knowledge on IVFP presentation and spontaneous recovery.
Main Methods:
- Systematic review of PubMed and Embase databases (1990-2023).
- Inclusion of studies on adult patients (≥18 years) with IVFP, excluding case studies and reviews.
- Extraction of data on demographics, symptoms, and spontaneous recovery.
Main Results:
- Analysis of 29 studies involving 1238 patients with IVFP (mean age 55.8 years).
- Unilateral IVFP occurred in 97.0% of cases, predominantly on the left side (67.5%).
- Common symptoms included dysphonia and dysphagia; spontaneous recovery averaged 31.6% over 139.4 days, with no treatment correlation.
Conclusions:
- A significant gap exists in research regarding IVFP presentation and outcomes.
- Viral upper respiratory infections (URIs) are a potential, though under-documented, factor in IVFP development.
- Further research is essential to elucidate the causes and optimize management of IVFP.
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