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Related Experiment Videos

A neural pathway for the shift response in the cat.

D I Hamasaki, G W Maguire

    Brain Research
    |June 24, 1985
    PubMed
    Summary

    The shift response, or McIlwain effect, is modulated by visual stimuli on the receptive field center or surround. Appropriate stimulation enhances the response, while inappropriate stimulation decreases it, suggesting a disinhibitory process.

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    Experimental eye research·1996

    Area of Science:

    • Neuroscience
    • Visual Perception
    • Sensory Processing

    Background:

    • The McIlwain effect, or shift response, is a phenomenon in visual neuroscience.
    • Understanding the mechanisms of the shift response is crucial for comprehending visual processing.

    Purpose of the Study:

    • To investigate how stimulation of the receptive field center (RFC) and surround affects the amplitude of the shift response.
    • To determine the relationship between the shift response and neuronal activity, including maintained and transient firing rates.

    Main Methods:

    • Eliciting the shift response by moving a large grating >15 degrees from the RFC.
    • Applying steady targets to the RFC and RF surround to modulate the shift response.
    • Analyzing the correlation between response amplitude and neuronal firing rates (maintained and transient).

    Main Results:

    • Appropriate stimulation of RFC or surround increased shift response amplitude; inappropriate stimulation decreased it in a graded manner.
    • Shift response amplitude correlated with transient peak firing rate, not maintained activity.
    • Strong shift responses could be blocked by inappropriate stimulation.

    Conclusions:

    • The shift signal appears to modulate a tonic signal within the receptive field.
    • The transient excitatory nature of the shift response suggests a disinhibitory neural process.
    • A potential neural pathway for the shift response has been proposed.

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