Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Hepatitis and pancreatitis due to indalpine].

Y Calmus, M Biour, F Bodin

    Gastroenterologie Clinique Et Biologique
    |March 1, 1985
    PubMed
    Summary

    Indalpine medication can cause liver injury, specifically hepatitis, and pancreatitis. Monitoring liver enzymes and amylase levels during indalpine therapy is recommended to ensure patient safety.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Transversal suture of the rectus abdominis muscle in DIEP harvesting to include more than one perforator: Technical note.

    Annales de chirurgie plastique et esthetique·2025
    Same author

    DIEP flap reconstruction for sacrectomy defects: Two case reports.

    Annales de chirurgie plastique et esthetique·2025
    Same author

    Satisfaction survey of secondary rhinoplasty among unilateral cleft lip and palate patients.

    Annales de chirurgie plastique et esthetique·2022
    Same author

    Unilateral cleft nose deformities at adulthood.

    Annales de chirurgie plastique et esthetique·2022
    Same author

    Covering of wound infection in hip arthroplasty with local cutaneous flaps.

    Annales de chirurgie plastique et esthetique·2022
    Same author

    [Deep inferior epigastric pedicle for microsurgical free flap transfer for contralateral thigh root coverage].

    Annales de chirurgie plastique et esthetique·2022

    Area of Science:

    • Hepatology
    • Gastroenterology
    • Clinical Pharmacology

    Background:

    • Indalpine is a medication with potential adverse effects on the liver and pancreas.
    • Adverse drug reactions require careful monitoring and prompt management.

    Observation:

    • Two cases of drug-induced hepatitis and one case of pancreatitis were observed in patients receiving indalpine.
    • Hepatitis presented either acutely with cholecystitis-like symptoms or was detected via biological tests, primarily showing cytolytic damage.
    • Pancreatitis onset was subtle, characterized by escalating pain and diffuse pancreatic lesions.

    Findings:

    • Both hepatitis and pancreatitis cases resolved favorably after discontinuing indalpine.
    • Elevated amylase levels (amylasemia) were noted in hepatitis cases, suggesting a potential link between indalpine and pancreatic enzyme elevation.
    • Hepatitis was predominantly cytolytic in nature.

    Implications:

    • Transaminase and amylase levels should be routinely monitored in patients undergoing indalpine therapy.
    • Early detection and intervention are crucial for managing indalpine-associated hepatotoxicity and pancreatitis.
    • This study highlights the importance of pharmacovigilance for indalpine to prevent severe gastrointestinal complications.

    Related Experiment Videos