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Updated: May 2, 2026

Multimodal 3D Printing of Phantoms to Simulate Biological Tissue
Published on: January 11, 2020
Investigation of the tissue equivalence of typical 3D-printing materials for application in internal dosimetry using
Ayse Karadeniz-Yildirim1, Handan Tanyildizi-Kokkulunk2
1Opticianry Program, Istanbul Aydın University, Florya, Bakirkoy, Istanbul, 34295, Turkey.
Abstract:
This study evaluates the dosimetric accuracy of PLA and ABS 3D-printed phantoms compared to real tissues using Monte Carlo simulations in radionuclide therapy.
Materials And Methods:
A phantom representing average liver and lung volumes, with a 10 mm tumor mimic in the liver, was simulated for radioembolization using 1 mCi Tc-99 m and 1 mCi Y-90. The dose distribution (DD) was compared across PLA, ABS, and real organ densities.
Results:
For Tc-99 m, PLA showed a + 5.6% DD difference in the liver, and ABS showed - 35.3% and - 40.9% differences in the lungs. For Y-90, PLA had a + 1.7% DD difference in the liver, while ABS showed - 34.2% and - 34.9% differences in the lungs.
Conclusion:
In MC simulation, PLA is suitable for representing high-density tissues, while ABS is appropriate for simulating moderately low-density tissues.

