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The gender paradox in sepsis: Exploring male vulnerability and female resilience
Jiyun Hu1, Shucai Xie1, Ya Liao1
1Department of Critical Care Medicine, Hunan Provincial Clinical Research Center for Critical Care Medicine, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Abstract:
The role of gender in sepsis outcomes remains controversial. Numerous epidemiological studies investigating gender-dependent clinical outcomes in sepsis have yielded conflicting evidence. While the literature varies, most studies indicate that male gender is associated with worse sepsis outcomes and survival. Understanding the gender's role in these processes provides valuable insights into potential therapeutic targets for sepsis.
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