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Visual evoked potentials among Indian patients with optic nerve disorders
Ruchi Kothari1, Sai Shanmukh Vemparala2, Siraj Muhammed Shafy3
1Department of Physiology, Mahatma Gandhi Institute of Medical Sciences, Sevagram, Wardha, Maharashtra, India.
Bioinformation
|March 17, 2025
Summary
Visual Evoked Potentials (VEP) significantly aid in diagnosing optic nerve disorders by detecting abnormal P100 latency and amplitude. This objective tool is crucial for early detection and management of vision impairments.
Area of Science:
- Ophthalmology
- Neuroscience
- Medical Diagnostics
Background:
- Optic nerve disorders are a major cause of visual impairment.
- Accurate diagnosis and treatment are essential for managing these conditions.
- Advanced diagnostic techniques like Visual Evoked Potentials (VEP) can improve outcomes.
Purpose of the Study:
- To profile common optic nerve disorders.
- To evaluate the diagnostic and prognostic role of VEP in these conditions.
- To assess VEP's utility in a rural tertiary care setting.
Main Methods:
- A study involving 100 patients with optic nerve disorders and 200 controls.
- Data collection through structured questionnaires, clinical examinations, and VEP testing.
- Statistical analysis using SPSS version 23.
Main Results:
- Optic neuritis, ischemic optic neuropathy, and glaucoma were the most common disorders.
- VEP showed statistically significant abnormalities in patients compared to controls.
- Patients exhibited prolonged P100 latency and reduced amplitude (p<0.001).
Conclusions:
- VEP is a valuable diagnostic and prognostic tool for optic nerve diseases.
- VEP provides objective and reproducible data.
- This facilitates early detection and effective management of optic nerve disorders.
