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Leukemic infiltration of the optic nerves: demonstration by computerized tomography
1Department of Radiology, Veterans Administration Hospital, Minneapolis, Minnesota.
Summary
Leukemic infiltration can enlarge optic nerves, as shown by computerized tomography (CT). Central nervous system radiation therapy may reduce this optic nerve enlargement in leukemia patients.
Area of Science:
- Neuro-oncology
- Ophthalmology
- Radiology
Background:
- Leukemic infiltration of the central nervous system (CNS) can affect ocular structures.
- Optic nerve involvement in CNS leukemia is a rare but significant complication.
Observation:
- Computerized tomography (CT) imaging revealed optic nerve enlargement in two patients due to leukemic infiltration.
- Follow-up CT scans were utilized to monitor changes in optic nerve size.
Findings:
- Leukemic infiltration was identified as the cause of optic nerve enlargement.
- A reduction in optic nerve size was observed following central nervous system radiation therapy in one patient.
Implications:
- CT imaging is a valuable tool for diagnosing optic nerve enlargement caused by leukemia.
- Central nervous system radiation therapy shows potential as a treatment to reduce optic nerve infiltration in leukemia.